Upper Midwest Environmental Sciences Center
Relatively rapid loss of lampricide residues from fillet tissue of fish after routine treatment
Vue, C., Bernardy, J. A., Hubert, T. D., Gingerich, W. H., and Stehly, G. R., 2002, Relatively rapid loss of lampricide residues from fillet tissue of fish after routine treatment: Journal of Agricultural and Food Chemistry, v. 50, no. 23, p. 6786-6789.
The selective sea lamprey (Petromyzon marinus) larvicide 3-trifluoromethyl-4-nitrophenol (TFM) is currently used to control parasitic sea lampreys in tributaries to the Great Lakes basin. The concentration and persistence of TFM and its major metabolite, TFM glucuronide (TFM-glu), was determined in fillet tissue of fish after a typical stream application. Rainbow trout (Oncorhynchus mykiss) and channel catfish (Ictalurus punctatus) were exposed to a nominal concentration of 12.6 nmol/mL TFM for about 12 h during a sea lamprey control treatment of the Ford River in Michigan. Concentrations of TFM and TFM-glu were greatest in the fillet tissues during the exposure period, with greater residues in channel catfish (wet wt; mean, 6.95 nmol/g TFM; mean, 2.40 nmol/g TFM-glu) than in rainbow trout (wet wt; mean, 1.45 nmol/g TFM; mean, 0.93 nmol/g TFM-glu). After the exposure period, residues in both species decreased by 90-99% within 6-12 h and were less than the quantitation limit (<0.03 nmol/g) within 36 h.
TFM, TFM glucuronide, sea lamprey, lampricide, rainbow trout, channel catfish, trout Oncorhynchus-mykiss, cultured rainbow-trout, 3-trifluoromethyl-4-nitrophenol TFM, glucuronide, pharmacokinetics, metabolism, testes