Vue, C., Bernardy, J. A., Hubert, T. D., Gingerich, W. H., and Stehly, G. R., 2002,
Relatively rapid loss of lampricide residues from fillet tissue of fish after routine
treatment: Journal of Agricultural and Food Chemistry, v. 50, no. 23, p. 6786-6789. 

Abstract

The selective sea lamprey (Petromyzon marinus) larvicide
3-trifluoromethyl-4-nitrophenol (TFM) is currently used to control parasitic sea
lampreys in tributaries to the Great Lakes basin. The concentration and persistence of
TFM and its major metabolite, TFM glucuronide (TFM-glu), was determined in fillet
tissue of fish after a typical stream application. Rainbow trout (Oncorhynchus mykiss)
and channel catfish (Ictalurus punctatus) were exposed to a nominal concentration of
12.6 nmol/mL TFM for about 12 h during a sea lamprey control treatment of the Ford
River in Michigan. Concentrations of TFM and TFM-glu were greatest in the fillet
tissues during the exposure period, with greater residues in channel catfish (wet wt;
mean, 6.95 nmol/g TFM; mean, 2.40 nmol/g TFM-glu) than in rainbow trout (wet wt;
mean, 1.45 nmol/g TFM; mean, 0.93 nmol/g TFM-glu). After the exposure period,
residues in both species decreased by 90-99% within 6-12 h and were less than the
quantitation limit (<0.03 nmol/g) within 36 h.

Keywords

TFM, TFM glucuronide, sea lamprey, lampricide, rainbow trout, channel catfish, trout
Oncorhynchus-mykiss, cultured rainbow-trout, 3-trifluoromethyl-4-nitrophenol TFM,
glucuronide, pharmacokinetics, metabolism, testes