Stehly, G. R., and Plakas, S. M., 1992, Disposition of 1-naphthol in the channel catfish
(Ictalurus punctatus ).: Drug Metabolism and Disposition, v. 20, no. 1, p. 70-73.

Abstract

The pharmacokinetics, tissue distribution, and metabolism of 1-naphthol were
examined in the channel  catfish (Ictalurus punctatus ). After oral dosing, peak plasma
concentrations of 1-naphthol occurred at 1 hr;  parent compound made up less than
15% of the total radioactivity, and the bioavailability was 32%. Plasma  protein
binding was 92% and was independent of concentration. 1-Naphthol and metabolites
were rapidly  eliminated from the tissues after oral dosing.

Keywords

fish-physiology, animal-metabolism, pharmacology, naphthol, Ictalurus-punctatus