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folder.gifAquaculture Drug Research and Development

Oxytetracycline - Reports

Human Food Safety - Efficacy - Target Animal Safety - Environmental Safety

Test system for oxytetracycline target animal safety studies with hybrid striped bass, walleye, and yellow perch.
Test system for oxytetracycline target animal safety studies with hybrid striped bass, walleye, and yellow perch.

Oxytetracycline medicated feed used during target animal safety trials.
Oxytetracycline medicated feed used during target animal safety trials.

Necropsy of yellow perch after treatment with oxytetracycline.
Necropsy of yellow perch after treatment with oxytetracycline.

Oxytetracycline being concentrated from fillet tissue extract on solid phase extraction columns.
Oxytetracycline being concentrated from fillet tissue extract on solid phase extraction columns.

Human Food Safety

Bernardy, J.A., C. Vue, and M.P. Gaikowski. 2000. Validation of an HPLC method for oxytetracycline in coho salmon and northern pike fillet tissue. Submitted to the U.S. Food and Drug Administration, Center for Veterinary Medicine, July 10, 2000. 1273 p.
Summary


Bernardy, J.A., C. Vue, and M.P. Gaikowski. 2000. Oxytetracycline residue depletion from walleye fillet tissue. Submitted to the U.S. Food and Drug Administration, Center for Veterinary Medicine, October 06, 2000.  1514 p.
Summary


Bernardy, J.A., C. Vue, and M.P. Gaikowski. 2000. Oxytetracycline residue depletion from northern pike fillet tissue. Submitted to the U.S. Food and Drug Administration, Center for Veterinary Medicine, October 06, 2000. 701 p.
Summary


Meinertz, J.R., M.P. Gaikowski, G.R. Stehly, and W.H. Gingerich. 1999. Oxytetracycline depletion from skin-on fillet tissue of coho salmon cultured and fed oxytetracycline medicated feed at water temperatures ranging from 4.1 to 8.5 °C. Submitted to the U.S. Food and Drug Administration, Center for Veterinary Medicine, January 29, 1999. 554 pages.
Summary


Meinertz, J.R. and G.R. Stehly. 1998. Liquid chromatographic determination of oxytetracycline in edible fish fillets from six species of fish. Submitted to the Upper Midwest Environmental Sciences Center archives, January 6, 1998. 221 pages.
Summary


Stehly, G.R. and J.R. Meinertz. 1997. A bridging study for oxytetracycline in the edible fillet of rainbow trout: Analysis by a HPLC method and the official microbiological method. Submitted to the U.S. Food and Drug Administration, Center for Veterinary Medicine, August 26, 1997. 364 pages.
Summary


Efficacy

Schmidt, L.J., Stehly, G.R., Myers, C.T., and P.A. Rudd. 1999. Efficacy of feed additive oxytetracycline treatments for Aeromonas hydrophila, bacterial coldwater disease, columnaris disease, and enteric redmouth disease in freshwater fish. Submitted to the U.S. Food and Drug Administration, Center of Veterinary Medicine, January, 1999.
Summary


Target Animal Safety

Gaikowski, M.P., J.C. Wolf, W.H. Gingerich, and W.J. Larson. 2003. Target Animal Safety of TM-100F Type A Medicated Article (220 g oxytetracycline/kg) Administered in Feed to Hybrid Striped Bass Morone chrysops x M. saxatilis, Walleye Stizostedion vitreum, and Yellow Perch Perca flavescens. Submitted to the U.S. Food and Drug Administration, Center for Veterinary Medicine, February 19, 2003. 861 pages.
Summary


Environmental Safety

Schmidt, L.J., Gaikowski, M.P., and W. H. Gingerich. 2004. An environmental assessment of the proposed use of oxytetracycline-medicated feed in freshwater aquaculture. Submitted to the Center for Veterinary Medicine, October, 2004. 78pp.
Summary

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